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Xu and colleagues discovered that Ficolin B, carried by exosomes from alveolar macrophages, exacerbates bleomycin-induced lung injury and fibrosis by promoting ferroptosis through the cGAS/STING signaling pathway [113]

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Supporting this, analyses of the coelomic fluid of black sea urchins ( Mesocentrotus nudus ), showed alanine as an alternative energy substate to food restriction 72

Using a 1:100 ratio of mg tissue to L KME buffer (20 mM MOPS, 120 mM KCl, and 1 mM EGTA, pH 7.4), tissue was homogenized in 2 s bursts separated by a 2 s rest for a total of 10 s (or 3 cycles) at 16,600 rpm using IKA T25 digital Ultra-Turrax homogenizer