This is also the case for those with exocrine pancreatic insufficiency (EPI)
Most report only a slight pinch
The main difference is not receptor target, but duration: DAC produces longer GH/IGF-1 signaling, while No DAC produces shorter GHRH-like signaling
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doi: 10.1016/j.cell.2011.12.017 179 SenguptaSBiarnesMCJordanVC