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Damaged dopaminergic neurons release matrix metalloproteinase 3, -synuclein, and neuromelanin that superactivated microglia, inducing reactive microgliosis, enhancing of the neurotoxicity-related mediators, such ROS (Figure 3)
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For non-diabetic research subjects, fasting glucose normalization was observed within the first 48 weeks of the escalation phase, even before maximum dose was reached
Check urine color aim for light yellow to clear
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