NICE recommended semaglutide 2.4 mg (TA875, 2023) for use within specialist Tier 3 weight management services in adults with a BMI of 35 kg/m (or 32.5 kg/m in people of South Asian, Chinese, other Asian, Middle Eastern, Black African, or African-Caribbean family background) with at least one weight-related comorbidity, or a BMI of 3034.9 kg/m in specific circumstances
Patients are advised to maintain adequate hydration, as dehydration can often trigger or worsen headaches
This plateau reflects the body reaching a new steady weight , not that the medication stopped working. Why Plateaus Happen The Metabolic Explanation A Smaller Body Needs Fewer Calories As weight decreases, your body naturally burns fewer calories at rest and during daily activity
New England J Med [Internet]
We also see that with bariatric surgery, where patients start to regain weight as well. One factor, he said, is the speed of early weight loss