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Glutathione consists of three amino acids: glutamate, glycine, and cysteine
Subsequent GLP-1RAs have been engineered by modifying human GLP-1 to increase similarity, extend duration (once-weekly options)
The word itself comes from the same root as restore reconstitution returns a dried compound to something close to its original liquid state
No diabetic retinopathy at baseline: typically annual exams, with earlier follow-up if high baseline A1c, large early A1c drop, or new symptoms Mild nonproliferative diabetic retinopathy: every six to twelve months, shorter intervals if rapid glucose changes or symptoms appear Moderate nonproliferative retinopathy: every three to six months Severe nonproliferative retinopathy: every two to three months Proliferative diabetic retinopathy or prior macular edema: individualized schedule, often every two to four months when stable, more frequent when starting treatment Starting semaglutide may justify scheduling one additional exam during the first six months in higher-risk patients to catch any early worsening
GLP-1 analog has 97% homology with human GLP-1 and has been approved for the clinical treatment of diabetes and obesity
