The same applies when choosing between an injection and an oral option like Wegovy
-SMA is produced by activated HSCs (myofibroblast-like cells) but not by resting (quiescent) HSCs, thereby a marker of HSC activation
In addition, IGF-IR inhibition sensitizes cancer cells to other chemotherapeutic agents, such as paclitaxel, 5-fluorouracil (5FU), temozolomide, gemcitabine, and bortezomib [101,102,103,104,105]
doi: 10.1038/s42255-023-00801-2 61 HallCJBoyleRHAstinJWFloresMVOehlersSHSandersonLEet al
Despite this, there are growing concerns over its serious side effects, including blood clots, DVTs, and pulmonary embolisms