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Type III hypersensitivity reaction results from drug and antibody immune complexities deposited in tissues (eg, cutaneous vasculitis, deposition and subsequent complement activation in the blood vessels of the skin leads to palpable purpura)

In December 2025, Rhythm Pharmaceuticals announced positive preliminary results from its exploratory Phase II trial of setmelanotide in patients with PWS

Bowen, J

Encouraging results: Novo Nordisks Wegovy, for example, has shown a 20% reduction in heart attack, stroke, or death from heart disease in recent trials