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To demonstrate specificity of the effect, we sought to rescue the decreased mEPSC frequency by pretreating with pyroglutamate (PGA), the precursor of glutamate that is synthesized downstream of GGT, which is blocked by acivicin (Fig
Treatments are HSA/FSA eligible, and hydration effects last approximately 34 days
This philosophical point matters for researchers designing longevity protocols
Understanding which profiles align best with the mechanism helps avoid wasted effort and expense
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