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The immune system relies heavily on specific vitamins, minerals, and antioxidants to function optimally

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methotrexate is often first-line, combined with short-term corticosteroids [18] [19] Biological therapies : TNF inhibitors (such as adalimumab, etanercept) or other biologics for inadequate response to conventional DMARDs JAK inhibitors : Newer oral medications like tofacitinib for refractory cases Regular monitoring : Blood tests to assess disease activity and medication safety Allied health professional input plays a crucial role: Physiotherapy : Exercise programmes, joint protection techniques, mobility aids Occupational therapy : Adaptations to daily activities, assistive devices, workplace modifications Podiatry : Foot care and orthotic provision for lower limb arthritis When to contact your GP : New or worsening joint pain, swelling, or stiffness Morning stiffness lasting more than 30 minutes (suggestive of inflammatory arthritis) Joint symptoms affecting daily activities or sleep Inadequate symptom control with current treatments Side effects from arthritis medications When to seek urgent medical attention : A hot, acutely swollen joint (possible septic arthritis) Joint symptoms accompanied by fever or feeling systemically unwell Patients can access NHS services through GP referral, and many areas offer self-referral to physiotherapy services (check local NHS provision)