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Long-term metformin therapy and vitamin B12 deficiency: an association to bear in mind
The pathophysiology of TN is multifactorial and involves genetic predisposition, anatomical changes, and neurophysiological factors, leading to hyperexcitable neuronal states, central sensitization and widespread neural plasticity changes
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Handle under nitrogen atmosphere where practical to limit oxidation of methionine-free but otherwise oxidation-sensitive residues during reconstitution
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