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Whitaker DL, Geyer-Kim G, Kim ED
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DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif:N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids.[5] In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH)
The regulation itself states that available data are inadequate to demonstrate the safety or efficacy of any drug product compounded using the substances listed there, or to establish general recognition of safety or effectiveness
The protective role of IF during inflammation in enhancing intestinal barrier function is accomplished through two main mechanisms
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