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The downstream sequence Gq/11 coupling, phospholipase C activation, IP3-mediated calcium mobilization, GH exocytosis is the same across all three compounds
Vairetti M, et al
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Structural models were calculated using modified CNS protocols in the ARIA/CNS setup 53,54 , similar as described for the FOXO4 FH -FOXO4 CR3 structure determination pipelne 42
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