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Administration Route: subcutaneous injection Site rotation: abdomen, thigh rotate Timing principles: Pre-bed dose aligns with natural nocturnal GH surge Fasted state is preferred (carbohydrate/insulin spikes blunt GH response) Space injections at least 3 hours from heavy meals Reconstitution Ipamorelin: 5 mg vial + 2 mL bacteriostatic water = 2,500 mcg/mL (200 mcg per 0.08 mL on U-100 insulin syringe = 8 units)