In the UK, suitability for approved weight management medicines is assessed in line with NICE guidance for example, NICE TA875 for semaglutide (Wegovy) and NICE TA820 for tirzepatide (Mounjaro) in type 2 diabetes which considers BMI thresholds, comorbidities, previous attempts at lifestyle intervention, and overall clinical context
This systematic review aimed to evaluate the potential effectiveness and safety of combination therapy of SGLT-2i and GLP-1 RA compared with monotherapy in individuals with type 2 diabetes
This article examines what the meta-analytic evidence actually shows, how berberine may work, how it compares to metformin, and what UK patients and clinicians need to know about safety, drug interactions, and the important limitations of current research
Saying "I have noticed my desire has changed since starting this medication, and I want to work through it with you" is infinitely more productive than silently withdrawing from intimacy and leaving a partner to wonder why
ISSN 0891-3668