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Work with a 25 mg dose for up to 14 weeks to optimize your weight loss therapy

Long-term dosing studies have also been conducted to evaluate tissue tolerance and inflammation markers, suggesting a favorable profile in terms of local joint impact and systemic safety

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A 2008 study published in the Journal of Medicinal Chemistry demonstrated metabolic effects in rodent models at 50mg/kg, which led early researchers to extrapolate human-equivalent doses between 50100mg daily