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According to a 2021 systematic review of eight studies, yohimbine (a component in yohimbe) alone had no significant effects on sexual function but may be beneficial when combined with other supplements

Conflict of interest BG has served as a consultant for AstraZeneca, Boehringer Ingelheim, Bristol-Myers Squibb, Merck (MSD) and Novartis as manufacturers of DPP-4 inhibitors and has received honoraria from these companies for lectures

doi:10.1002/ptr.4916

Most preclinical studies utilize supraphysiologic doses, alternate routes of administration and short follow-up windows that do not mimic human reproductive timelines