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Adems, conviene tomar precauciones frente a la deshidratacin (que puede sobrevenir por algunos de los efectos secundarios gastrointestinales de la semaglutida), prestar atencin a dolores de estmago continuados e intensos (que pueden ser sntoma de la pancreatitis aguda, una complicacin grave de la diabetes), ante los sntomas de la enfermedad ocular diabtica (que puede empeorar con la toma de semaglutida) y ante los sntomas de la hipoglucemia (que puede volverse ms comn cuando la semaglutida se usa frente a otros medicamentos)
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2.1% (consistent with weight loss rate) No Safety Signals: No increased risk of pancreatitis, thyroid tumors, or major CV events Historic Achievement: REDEFINE-1 demonstrated that CagriSema produces the highest mean weight loss (22.7%) ever reported for an obesity pharmacotherapy in a Phase 3 trial
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In a retrospective study, Lyons et al., evaluated the effects of semaglutide in 30 obese patients with HS, reporting reductions in weight, BMI, and metabolic markers such as HbA1c, along with improvements in DLQI and a decreased frequency of flares [160]
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