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Do not increase doses faster than prescribed, as this worsens gastrointestinal side effects

In many cases: GGT drops within 48 weeks Oxidative stress markers improve Insulin sensitivity improves Weight Optimization Weight loss reduces: Hepatic fat Inflammation Insulin resistance GGT levels Even modest weight reduction has measurable effects

Stacking agonists amplifies GI side effects without proportional clinical benefit

If you have a history of eating disorders: This is a critical conversation

And nothing grabs attention quite like the idea that a wildly popular medication might be secretly causing some terrible health problem