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Compound 6 exhibited only marginal efficacy of 16% and 7% decrease in worm and egg burdens, respectively
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This approach benefits from its specificity, self-amplifying nature, and proposed safety due to the narrow host range of phages
Conversely, ALC boasts an added acetyl group that enables it to cross the blood-brain barrier
Those ligand-target bindings would include benzodiazepine, opioid, (1)- and (2)-adrenergic, serotonergic and cholinergic receptors 85 and, notably, the fascinating issue of the anti-nociceptive role of melatonin seems to be mediated by MT1 and MT2 receptors themselves 86 , 87,88
