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In this analysis, we included the negative allosteric modulators NNC0640 (PDB: 5VEX) and PF-06372222 (PDB: 6KJV), the peptide agonists GLP-1 (7-36) (PDB: 6X18), exenatide (PDB: 7LLL) and semaglutide (PDB: 7KI0) as well as the small molecule agonist danuglipron (PDB: 6X1A) (Supplementary Data 1)
The relationship between dose and response in humans is unknown
Gene ij is the log 2 expression value for sample i in patient j for a single gene
To reduce the risk of infection, always use new sterile unused needles and syringes for each injection
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