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It's temporary per session but cumulative with regular treatment.

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Safety and effectiveness of dulaglutide in the treatment of type 2 diabetes mellitus: A Korean Real-World Post-Marketing study

In Ringer solution, when the hematocrit was adjusted to 4%, PS exposure was not significantly different, although it was around half the level of PS exposure seen in the 0.4% hematocrit condition

It is an antioxidant in plants, animals, fungi, and some bacteria and archaea