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Metformin primarily reduces glucose production in the liver and improves insulin sensitivity
I had lost weight while on Avonex and got to 16 stone 10 but my weight had crept back up or 18 stone 12lbs by mid-2023 for no obvious reason, and from that point I couldnt lose or gain weight
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This occurs through the phosphorylation of myosin light chain (MLC) by ROCK, resulting in cytoskeletal reorganization and changes in endothelial cell adhesion
Knowing what your plan covers before committing avoids frustrating mid-treatment switches
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