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33 CONCLUSION While these findings are encouraging, especially for diseases such as psoriasis and HS in which patients often are heavier and may have comorbidities like type 2 diabetes, insulin resistance, or metabolic syndrome, its important to recognize that most data to date come from small observational or retrospective studies with multiple possible confounders

Code availability The analytic code is available at Change history 31 January 2025 A Correction to this paper has been published: References Pfeffer, M