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Unfortunately, GLP-1 is rapidly degraded by the enzyme dipeptidyl peptidase-4 (DPP-4), which limits the therapeutic efficacy of native GLP-1 (Deacon et al., GLP-1R agonists The GLP-1R agonists mediate their action by acting directly on the GLP-1R
10.1136/gut.52.6.834 Gut 143 RoccaA
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These changes resulted in the dismissal of three C-level executives, as well as 8,000 employees, as the company aimed to transform into a leaner organization
The primary concern is the combined glucose-lowering effects of these drugs
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