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The glucagon-like peptide-1 receptor agonist (GLP-1 RA) is already approved for use in the treatment of obesity and for weight management

The number of people taking weight-loss injections is exploding

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Conclusion and perspective Emerging preclinical evidence suggests that GLP-1 receptor agonists (GLP-1RAs) may represent a novel class of therapeutics for pain management

These considerations support the physiological relevance of the observed temperature-dependent modulation of T-cell motility and metabolic adaptation