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Mylans challenges target these extensions, arguing that secondary patents, like those for dosage regimes, may be invalid if deemed obvious over prior art, such as Novos earlier GLP-1 drug liraglutide (Reddie & Grose, August 30, 2024)

The weight loss produced by these compounds, even in the most favorable studies, amounts to approximately 2-4 pounds over 8-12 weeks

Hemoglobin A1c levels tend to rise within weeks to months after discontinuation, returning toward pre-treatment values

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