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DIRECT PARTICLE SIZE DISTRIBUTION MEASUREMENT OF AN ACTIVE INGREDIENT SUSPENDED IN PRESSURISED METERED DOSE INHALERS AND PARAMETERS, WHICH INFLUENCE MIGRATION RATE Cristina Rey Blanes1 , Luca Serratore1, Katie Reichwald1, William J Ganley1, Jose Ferrao2, MarieLaure Vicenty2, Guillaume Lemahieu3, Matthias Sentis3, Giovanni Brambilla3, Robert Price1, Jagdeep Shur1 and Irene Rossi1 1Nanopharm, An Aptar Pharma Company, Grange Road, Cwmbran, NP44 3WY, United Kingdom 2Aptar Pharma, Route des Falaises, Le Vaudreuil, 27100, France 3Formulaction, 35 Rue Paule Raymondis, Toulouse, 31200, France Summary: pMDIs make up 70% of inhalers used in the United Kingdom

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