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Arch Neurol 46:543548

These include: Nausea (very common, affecting more than 1 in 10 people) Diarrhoea (common, affecting up to 1 in 10 people) Vomiting (common) Constipation (common) Abdominal pain and discomfort (common) These gastrointestinal effects create the conditions for dehydration , which subsequently causes urine to become concentrated and darker

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[35] Human studies in which parenteral glutathione was administered for male infertility (600 mg/day glutathione intramuscularly for two months), or given to enhance insulin secretion in people with impaired glucose tolerance, did not report any significant adverse effects