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had taken a glucagon-like peptide-1 (GLP-1) receptor agonist medications for the treatment of type 2 diabetes or, increasingly, for weight loss
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During this critical window, many patients reduce their food intake substantiallysometimes more than intendedbecause appetite suppression becomes profound
Starting in the 1920s, people began taking 2,4-Dinitrophenol (DNP) which caused dramatic weight loss by making mitochondria less efficient (see our Mitochondria May blog post for more information)
Generally, it can take 4 to 12 weeks of consistent use to notice changes in skin brightness or energy levels
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