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| Concentration | BAC Water | Doses at 0.5mg | Doses at 1.0mg | |---------------|-----------|----------------|----------------| | 5mg/mL (recommended) | 1.0mL | 10 doses | 5 doses | | 2.5mg/mL | 2.0mL | 10 doses | 5 doses | **Best practice:** Use 1.0mL BAC water (5mg/mL)
Insulin resistance occurs when human cells respond inadequately to insulin, impairing their ability to efficiently absorb and store glucose from the bloodstream
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Important patient safety considerations include: GLP-1 receptor agonists are currently licensed only for type 2 diabetes and, for specific products, weight managementnot for neurological conditions Common side effects include nausea, vomiting, diarrhoea, and constipation, which usually improve over time Patients should seek urgent medical help for symptoms suggestive of pancreatitis (severe, persistent abdominal pain, often radiating to the back, with or without vomiting) Gallbladder problems including gallstones and inflammation may occur Risk of hypoglycaemia is increased when used with insulin or sulfonylureas Diabetic retinopathy complications may occur with semaglutide, particularly with rapid improvement in blood glucose control [26] [27] Severe gastrointestinal side effects may lead to dehydration and acute kidney injury These medications are not recommended during pregnancy or breast-feeding [25] [1] Patients should report any suspected side effects via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk or the Yellow Card app)
