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More sensitive than SPEP (e.g., an SPEP could be negative, however the immunofixation could show a monoclonal protein) Serum Free Light Chains (FLC) Measure serum free light chains (kappa or lambda) that are unbound to immunoglobulins (aka antibodies)
The cycle does not reset from day 1
Many calculators also account for body composition by using your lean mass or goal weight (rather than total body weight) if you have a higher body fat percentage, to avoid overestimating your needs
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