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Examples include people with PCOS, Crohns disease, certain forms of depression or anxiety tied to metabolic signaling, and patients with persistent inflammation where weight loss isnt the primary goal

Reduced NNMT in adipose tissue was associated with increased expression of polyamine flux genes and increased adipocyte energy expenditure connecting NNMT inhibition to "futile cycling" mechanisms that consume energy without productive metabolic output

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But others could face more serious issues like: Prolonged bleeding from cuts or injuries Nosebleeds (epistaxis) Gingival bleeding Menorrhagia in women In severe cases, gastrointestinal or intracranial bleeding Spotting these symptoms early is key