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GLP-1 RA class of drugs and their mechanism of action GLP-1 RA (Glucagon-like peptide-1 receptor agonists) are a group of drugs used in the treatment of type 2 diabetes

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Semaglutide, however, has the most mature cardiovascular outcomes evidence in adults with overweight or obesity and established cardiovascular disease without diabetes because SELECT demonstrated a reduction in MACE

doi:10.1016/s0024-3205(00)00803-1

Most healthcare providers recommend at least 1,200 to 1,500 calories daily for women and 1,500 to 1,800 for men during semaglutide treatment