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Yi xue ban = Journal of Zhejiang University

The answer is pituitary desensitization, or downregulation

Treatment typically begins at a low dose and increases over time through a process known as GLP-1 dose titration

Data extraction and quality assessment were performed, focusing on primary outcomes, including changes in triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and very low-density lipoprotein (VLDL), and secondary outcomes including blood pressure (BP) and body mass index (BMI)

IGF-1 signaling is mitogenic and anti-apoptotic both relevant to cancer biology