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Its water-soluble derivative, sodium Tan IIA sulfonate injection (STS), is widely used in the clinic as an adjuvant drug for coronary heart disease, myocardial infarction and heart failure in China [153]

Although these data appear to conflict with our observation that tirzepatide stimulates alpha cell activity, it is important to note that the metabolic profile of the subjects in the tirzepatide arm improved dramatically during the 28-week period, complicating interpretations

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