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Surgery also alters how food, bile, and pancreatic enzymes are mixed and reduces pancreatic volume.7 Whipple procedures (which remove the head of the pancreas, the first part of the duodenum, the gallbladder, and the bile duct) performed to treat pancreatic cancer led to the highest rates of EPI at 85% to 95% of patients.7 Cystic Fibrosis CF is another disease associated with EPI as the pancreas becomes surrounded by a thick mucus and cannot function adequately due to genetic mutations.7 It is estimated that 85% of those with CF have pancreatic insufficiency, and that even those who are considered pancreatic sufficient still have some degree of abnormal pancreatic function.6 The pancreatic function in those individuals may deteriorate over time

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If you cannot verify the complete thermal history of a vial from the moment it was lyophilized to the moment it's administered, you cannot verify its potency

[51] [57] [58] See also [edit] References [edit] Current diagnosis & treatment in gastroenterology