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Both semaglutide and tirzepatide belong to this class of medications, but they work in slightly different ways
552561, Nov
Along this line, a recent meta-analysis of 11 heterogeneous observational studies primarily consisting of pharmacovigilance and cohort studies reported no significant difference in suicidal outcomes between GLP-1 RAs compared with other anti-hyperglycemic drugs (RR:0.568, 95% Cl:0.077-4.205) [27]
Researchers also cannot establish causality for outcomes, since they would not have a placebo group
Subjective improvement without objective measurement is insufficient for evaluating response
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