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"Scientists have had a hard time getting this drug into the body where it didn't get broken down in the GI tract by the stomach acid," Egan said
Promoter polymorphisms in glutathione-S-transferase genes affect transcription
It was a twice-daily injection, and the proof of concept was clear: you could safely lower blood sugar, and patients tended to lose some weight along the way
While moderate weight reduction may yield metabolic benefits, rapid or sustained weight loss is frequently associated with decreased bone mineral density, deterioration of bone microarchitecture, and heightened fracture risk
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