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Ipamorelin binds the GHS-R1a receptor and triggers pulsatile growth hormone release through that pathway, without producing measurable elevations in cortisol, prolactin, or aldosterone in published preclinical and early human studies
10.1523/JNEUROSCI.6326-11.2012 J
Participants receiving the optimal dose lost an average of 2.6 kg more than the placebo group
Trackable markers, such as weekly weight changes, fasting glucose levels, and a simple symptom score, make that decision objective, not guesswork
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