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While antioxidant systems can mitigate oxidative injury to healthy tissues during breast cancer treatment, indiscriminate use of exogenous antioxidant supplements during ROS-dependent therapies such as anthracycline chemotherapy and radiotherapy may theoretically reduce treatment efficacy by protecting malignant cells from oxidative damage

Nevertheless, factors such as supply challenges, restricted funding, high out-of-pocket costs and side effect fears could limit the uptake of the drugs, creating uncertainties around the future size and shape of demand

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A true plateau means zero weight loss over an extended period