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Effect of the optimized quaternary SSPH-MPN on liver oxidative enzymes To determine the activities of SOD, GSH-Px, MDA, and T-AOC in liver, the liver homogenates of apoE / mice after treatment of different samples for 12 weeks were used for the analysis of the antioxidant enzymes activity by using the commercially available kits according to the manufacturers instructions (Jiancheng Bioengineering Institute, China)

This is likely due to the fact that MT-1 has a much shorter half-life than MT-2 at around 1 hour and its effects are much more short-lived

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