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The current major treatment of PD supplies the deficiency of dopaminergic neurotransmitters and/or reduces the degradation of dopaminergic neurotransmitters in the synaptic gap of the striatum, or the use of dopaminergic agonists to model dopaminergic neurotransmitters to stimulate the dopaminergic receptor to relieve the symptoms and signs, mainly consisting of compound levodopa agents (dopaminergic neurotransmitter supplemental drugs), monoamine oxidase B and catecholamine O-methyltransferase (dopaminergic neurotransmitter degradation inhibiting drugs), and dopaminergic receptor agonists (directly stimulating dopaminergic receptor drugs) (4)

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Slow or Non-Responders: Not everyone experiences dramatic benefits