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FAK is vital in the mechanotransduction-regulated biogenesis of myocardial mitochondria
Science (1993) 261(5120):4669.10.1126/science.8101391 56 MorimotoCSchlossmanSF
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Options at plateau include maintaining the current dose to prevent regain (the STEP 4 trial showed rapid weight regain after discontinuation), adding structured exercise to increase energy expenditure, reviewing dietary quality rather than just quantity, and in some cases, considering a temporary dose increase if prescribed by a provider
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