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Because this study was designed as a targeted genomic characterization of CTX-Massociated isolates rather than a comparative casecontrol analysis, ceftriaxone-susceptible isolates were not included, limiting direct comparisons between CTX-Mpositive and CTX-Mnegative populations

Mitochondrial and Energy Production Markers: These include metabolites like citric acid, fumaric acid, and aconitic acid from the Krebs (citric acid) cycle

This combination therapy improved myeloid cell antigen presentation, decreased immune suppression by MDSCs, promoted T-cell activation, and decreased its quiescence