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Co-administration of SGLT2 inhibitors with GLP1-RA reduces body weight by 4.5 kg at 24 weeks of treatment, and this weight loss is maintained for up to 1 year ( 5.7 kg) in obese individuals without diabetes [21, 30]
c represents the number of reports without target drug exposure but with target AEs
The study demonstrated noninferiority to placebo and thus cardiovascular safety, but superiority was not evident [5,10]
R., Lingvay, I., Ludemann, J., Andreassen, C., Navarria, A., & Viljoen, A
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