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This escalation approach is standard across GLP-1 class compounds and serves to improve gastrointestinal tolerability
Higher Protein diets, Less Hunger This effect may be related to the GLP1 effect of the dietary protein and is particularly noticeable at breakfast and dinner
Currently OCA is being evaluated in a large phase III, randomised, placebo-controlled trial termed REGENERATE
Many patients may be able to restart treatment after medical evaluation, depending on their health status and treatment goals
There is no clinical data on this combination
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