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Strinic, D., et al

While scientists dont know exactly how caffeine works in the brain, the running theory is that it binds to adenosine receptors, preventing a typically adenosine-induced slowdown of wake-promoting brain regions

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This imbalance can damage cells, proteins and DNA, leading to various health issues

This premature breakdown can lead to the release of byproducts that irritate the stomach lining, leading to that "pain" or "heavy" feeling