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On the other hand, their pleiotropic actions, frequent involvement of the central nervous system, and context-dependent effects have historically rendered them unattractive as therapeutic targets
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10.3389/fimmu.2023.1223096 35
Cellular senescence and SASP in tumor progression and therapeutic opportunities
Each site has different equipment, utilities, and even microenvironments, so even minor differences (temperature gradients, mixing dynamics) must be harmonized
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