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However, high doses of fiber supplements such as psyllium, glucomannan, or konjac may worsen gastrointestinal symptoms in people using GLP-1 medications
Figure 2 GLP-1 GLP-1 is a highly regulated, post-translational product of proglucagon in the gut, secreted primarily in response to nutrient uptake, as its plasma concentrations are very low in the fasting state (42)
It creates new blood vessels, stimulates fibroblast activity, upregulates growth factor sensitivity, and directly repairs mucosal tissue
Oral vs Injectable: Why the Pill Matters The oral formulation of semaglutide, approved by the FDA, uses an absorption enhancer to protect the medication through the digestive system