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Recombinant LONP1 delivered via intravesical or oral routes slows tumor progression and improves survival in c-MYC-dependent bladder and colorectal cancer mouse models, mediated by time-dependent degradation of c-MYC

Therapeutic applications of Dihexa focus on comprehensive cognitive enhancement, memory optimization, learning capacity improvement, age-related cognitive decline prevention, and neurological recovery support

Cases against Mylan and Sun Pharmaceuticals, at least, remain pending

For example, a DNA repair protein, redox factor Ref-1, was reported to promote the DNA-binding activities of several transcription factors, including HIF-1 and p53, which confers cytoprotective function under hypoxia

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